Can I disable share lending for a security?

No, unfortunately it is not possible to disable share lending with respect to the protection and hypothecation rules of the SEC or the Stock Yield Enhancement Program for an individual security. The only way to prevent a security from being lent is by owning all of your securities outright (no margin loan) and by not participating in the Stock Yield Enhancement Program. 

Additional Information

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Why are my shares not being lent, even though I am enrolled in the Stock Yield Enhancement Program (SYEP)?
Will IBKR lend out all eligible shares?
Does SIPC provide coverage for securities loaned out under the Stock Yield Enhancement Program?
Will IBKR lend out all eligible shares?