From both Mosaic and Classic TWS you will need to access Global Configuration and select Presets in order to create, edit, or remove presets for your orders.
When configuring Hotkeys in TWS, some drop-down menus allow you to choose "Default". For example, you can set your order size to be "Default", "Absolute" or "Available". If you select "Default", TWS will use the values defined in your Order Presets…